Mucormycosis in a diabetic.
نویسندگان
چکیده
Mucormycosis is an acute, often fatal intection caused by saprophytic fungi, of the order Mucorales. It occurs in debilitated patients who are compromised immunologically due to uncontrolled diabetes lymphoma, corticosteroid treatment and radiotherapy (Jain et al., 1978). Only 13 cases were reported up to 1963 (Pilsbury and Fischer, 1977). The fungus appears in tissues as hyphae which are irregular, non-septate and tend to branch nearly at right angles. It gains access by inhalation, involves palate, pharynx and nasal mucosa by contiguous spread and leads to infarction and gangrene of the sites involved (Abramson, Wilson and Arky, 1967). It may later spread to the paranasal sinuses, cribiform plate, meninges and brain. Mucormycosis of the paranasal sinuses and orbit has been reported to occur rarely without gross cerebral lesions (Baker and Durham, 1957); these cases are the ones that more often recover and the following case belonged to this category.
منابع مشابه
Case series of rhinocerebral mucormycosis occurring in diabetic patients
Background: Rhinocerebral mucormycosis is a fatal infection typically affecting diabetic or immunosuppressed patients. In most cases, infection is caused by inhalation of fungal spores. Mortality rate of patients is very high (40-85%). Case Presentation: In this study, three diabetic patients with rhinocerebral mucormycosis were presented. The etiologic agents of mucormycosis in two patien...
متن کاملPulmonary mucormycosis in patients with diabetic ketoacidosis: a case report and review of literature.
Mucormycosis is a rare opportunistic devastating fungal infection, which usually occurs in immunocompromised patients. Mucormycosis has multiple presentations that the predilection for one of these presentations varies with the either underlying or predisposing condition. We present a case of pulmonary and rhinocerberal mucormycosis in 56-year-old man with diabetic ketoacidosis.
متن کاملInvasive rhino-orbito-cerebral mucormycosis in a diabetic patient – the need for prompt treatment
Mucormycosis is a rare life threatening fungal infection predominately seen in immunocompromised or diabetic patients. The following case is of a known type II diabetic patient who presented with sepsis and sudden unilateral loss of vision secondary to infective rhino-orbito-cerebral mucormycosis. Treatment of the condition required extensive surgical intervention and medical management for a l...
متن کاملCase series of rhinocerebral mucormycosis occurring in diabetic patients
BACKGROUND Rhinocerebral mucormycosis is a fatal infection typically affecting diabetic or immunosuppressed patients. In most cases, infection is caused by inhalation of fungal spores. Mortality rate of patients is very high (40-85%). CASE PRESENTATION In this study, three diabetic patients with rhinocerebral mucormycosis were presented. The etiologic agents of mucormycosis in two patients we...
متن کاملMucormycosis: A Lethal Phenomenon in COVID-19 Patients: A Review of Diagnostic and Therapeutic Approaches
Coronavirus disease 2019 (COVID-19) has seriously spread worldwide. One of the problems of COVID-19 patients is co-infection with other microbial infections such as fungal infections that are severely life-threatening. Mucormycosis, one of these opportunistic fungal diseases that is mistakenly known as black fungal disease, has been reported in Iran and the world. This non-systematic review is ...
متن کاملThe endothelial cell receptor GRP78 is required for mucormycosis pathogenesis in diabetic mice.
Mucormycosis is a fungal infection of the sinuses, brain, or lungs that causes a mortality rate of at least 50% despite first-line therapy. Because angioinvasion is a hallmark of mucormycosis infections, we sought to define the endothelial cell receptor(s) for fungi of the order Mucorales (the fungi that cause mucormycosis). Furthermore, since patients with elevated available serum iron, includ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Postgraduate medical journal
دوره 58 686 شماره
صفحات -
تاریخ انتشار 1982